When I was in 6th grade, my class took a camping trip up to a forested section of the state for a few days. We were all divided into small groups of 4-5, with my friends all together in one group while I was stuck in another with a bunch of other kids I didn't know all that well. My group didn't like me that much, so when we all went stargazing one night, they collectively ditched me while I was looking through a telescope and went back to their cabin. I wound up getting lost by myself in the woods for a while trying to find them, and only made it back to our cabin later that night when my friends found me wandering around and walked me home themselves. The fact that they were a lot more caring made me wonder why the teacher hadn't put me in their group instead...
Outside of that, there have probably been at least a few times we've gotten lost while driving - usually while visiting cities for the first time, traveling out of state, etc.