Well for me the hardest part of doing an LP its to keep the daily upload of it while still uploading other series. But its not that hard either. Cause for me commentary its easy, i can talk and play and i give opinions about anything, i try jokes even if they are bad, someone always finds them funny, and i interact a lot with my subs. But as most of you said, it is all about getting used to it, you guys that have problems with that, you will get used to it with time. And at first i hated my voice too but now i actually dont mind it and i think it is a pretty normal voice. xD As for the editing part, i find it really easy, cause on sony vegas i save presets of everything and i basically just need to load the preset and it will appear for the most edited already, just need to make any layout changes for games like Pokémon and thats it. I take like from 1 to 5 min to edit. xD And my rendering is always the same time as the video itself, like if i record 22min it will take 22min of render. So quite easy to do the videos for me. =) If there is really something else that i find hard sometimes is to pay attention on a battle and talk about something at the same time when its a pokemon nuzlocke lol i already lost some pokemon cause im talking and i spam A. xD
And most fun part of it, is the interaction with the people that watch your series, having people leaving comments and replying to them on the actual video is really cool, and when you play a game that you know people are enjoying to watch and they comment on it, it gives you a lot of motivation to do it. Not to mention that i like challenges so for me any hard type of nuzlocke or rom hack makes me excited to play it! xD